Ran Reshef, MD

Expertise in: 
Blood and Marrow Stem Cell Transplantation, Hematology/Oncology
Accepting New Patients
Virtual Visits/Telehealth
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Overview

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Dr. Reshef trained in Hematology, Oncology and Bone Marrow Transplantation and received a Master of Science degree in Translational Research from the University of Pennsylvania. He joined Columbia University in 2015 as Director of Translational Research for the Blood and Marrow Transplantation program. He is the Clinical Lead for the CAR-T Cell Program at Columbia, a principal investigator at the Columbia Center for Translational Immunology and a member of the Herbert Irving Comprehensive Cancer Center.

Areas of Expertise / Conditions Treated

  • Amyloidosis
  • Bone Marrow Transplant
  • Cancer Immunotherapy
  • Cellular Therapy
  • Leukemia
  • Lymphoma
  • Multiple Myeloma

Academic Appointments

  • Associate Professor of Medicine at CUMC

Administrative Titles

  • Director, Translational Research, Blood and Marrow Transplantation
  • Clinical Lead, CAR-T Cell Program

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

Languages

  • Hebrew

Gender

  • Male

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Virtual Visits/Telehealth

Virtual Visits allow you to connect with your provider from the comfort, convenience, and safety of your own home.

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Phone Appointments

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Location(s)

161 Fort Washington Avenue
New York, NY 10032

Insurance Accepted

Aetna

  • Aetna Signature Administrators
  • EPO
  • HMO
  • Medicare Managed Care
  • NYP Employee Plan
  • NY Signature
  • POS
  • PPO
  • Student Health

Affinity Health Plan

  • Essential Plan
  • Medicaid Managed Care

AgeWell

  • Medicare Managed Care
  • Special Needs

Amida Care

  • Special Needs

Cigna

  • EPO
  • Great West (National)
  • HMO
  • POS
  • PPO

Emblem/GHI

  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross/Blue Shield

  • EPO
  • HMO
  • Medicare Managed Care
  • PPO

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Fidelis Care

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care
  • Medicare Managed Care

Healthfirst

  • Child/Family Health Plus
  • Leaf (Exchange)
  • Medicaid Managed Care
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare

Medicare

  • Railroad
  • Traditional Medicare

Multiplan

  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • HMO
  • Medicaid Managed Care

Oxford Health Plans

  • Freedom
  • Liberty

RiverSpring

  • Special Needs

UnitedHealthcare

  • Columbia University Employee Plan
  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

VNSNY CHOICE

  • Medicare Managed Care
  • SelectHealth
  • Special Needs

WellCare

  • Medicaid Managed Care
  • Medicare Managed Care

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • MD, 2003 Medicine, Sackler School of Medicine, Tel Aviv University (Israel)
  • MSc, 2011 Translational Research, Perelman School of Medicine University of Pennsylvania
  • Internship: 1998 Tel Aviv Sourasky Medical Center, Israel
  • Residency: 2007 Tel Aviv Sourasky Medical Center, Israel
  • Fellowship: 2009 Perelman School of Medicine University of Pennsylvania

Honors & Awards

  • Sternberg Research Award, Abramson Cancer Center, University of Pennsylvania (2008)
  • Bradley Fellow Research Award, Department of Medicine, University of Pennsylvania (2011)
  • Austrian Junior Faculty Award, Department of Medicine, University of Pennsylvania (2012)
  • Amy Strelzer Manasevit Award for the Study of Post-Transplant Complications, National Marrow Donor Program (2013)

Research

The Reshef lab combines efforts in both basic research and clinical investigation to advance the understanding of immune responses following hematopoietic stem-cell transplantation and other forms of cell therapy.

The lab is focused on two primary areas:

1. Investigating lymphocyte migration mechanisms and how they affect the clinical and immunologic outcomes of stem-cell transplantation. The lab pioneered the use of chemokine receptor blockade after allogeneic stem-cell transplantation to reduce immune-mediated complications.

2. Developing methodologies for the study of human samples from transplant recipients at the single-cell level in order to unravel novel immunologic mechanisms that would lead to new therapeutic approaches. The lab works with blood, stool and tissue samples and uses a diverse toolset that includes genomic and immunophenotypic methods to identify new therapeutic modalities. Our ultimate goal is to identify new targets that improve transplant outcomes using evidence in both mice and humans and to test these targets clinically.

Dr. Reshef’s research is funded by the National Cancer Institute, Conquer Cancer Foundation, National Marrow Donor Program and Department of Defense. He previously received awards from the Leukemia & Lymphoma Society and the American Society of Hematology.

Selected Publications

  1. Reshef R, Luger SM, Hexner EO, Loren AW, Frey NV, Nasta, SD, Goldstein SC, Stadtmauer EA, Smith J, Bailey S, Mick R, Heitjan DF, Emerson SG, Hoxie J, Vonderheide RH, Porter DL (2012). "Effect of Blocking Lymphocyte Chemotaxis on Visceral Graft-vs-Host Disease." N Engl J Med 367:135-145
  2. Reshef R, Huffman AP, Gao A, Luskin MR, Hexner EO, Loren AW, Frey NV, Stadtmauer EA, Luger SM, Mangan JK, Nasta SD, Gill SI, Sell M, Kambayashi T, Richman LP, Vonderheide RH, Mick R, Porter DL (2015). "High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection In Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning" J Clin Oncol 33:2392-2398.
  3. Ryan H. Moy, Austin P. Huffman, Lee P. Richman, Lisa Crisalli, Ximi K. Wang, James A. Hoxie, Rosemarie Mick, Stephen G. Emerson, Yi Zhang, Robert H. Vonderheide, David L. Porter and Ran Reshef (2017) "Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis" Blood 129:906-916
  4. Mishkin AD, Mapara MY, Reshef R (2018). "Iatrogenic Infertility After Curative Stem Cell Transplantation in Sickle Cell Disease Patients". Ann Intern Med 2018 Jun 19;168(12):881-88